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Recent studies have revealed a well-defined higher order of chromosome architecture, named chromosome territories, in the human sperm nuclei. The purpose of this work was, first, to investigate the topology of a selected number of chromosomes in murine sperm; second, to evaluate whether sperm DNA damage has any consequence on chromosome architecture. Using fluorescence in situ hybridization, confocal microscopy, and 3D-reconstruction approaches we demonstrate that chromosome positioning in the mouse sperm nucleus is not random.

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Mammalian sperm RNA has recently received a lot of interest due to its involvement in epigenetic germline inheritance. Studies of epigenetic germline inheritance have shown that environmental exposures can induce effects in the offspring without altering the DNA sequence of germ cells. Most mechanistic studies were conducted in laboratory rodents and C.

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Have you had genetic testing done and need a donor screened for a specific condition? How many vials do I need? Why should I think about storing vials?

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The microscope's ability to track this motion could help explain the key physical attributes of healthy and defective sperm. The ability to track this motion could help explain the key physical attributes of healthy and defective sperm. Most conventional microscopes in laboratories and clinical settings can only observe sperm's movement in two dimensions across a very small sample volume.

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September 14, Scientists have been observing sperm cells since the invention of the optical microscope. But surprisingly little has been known about sperm swimming patterns in 3-D — information that could help and improve scientists' understanding of the biophysics of sperm locomotion, which can shed light on key physical attributes of healthy and defect sperm.

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Researchers compared mutation rates in sperm and eggs for multi-sibling families, confirming that fathers contribute more mutations to their children than mothers. They revealed for the first time that the rate at which mutations in sperm accumulate with age varies from father to father. The study has important medical implications for predicting the risk of a second child inheriting a disease-causing mutation from its parents.

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Sperm morphological and morphometric evaluation in captive collared peccaries Pecari tajacu. Sousa; Erika A. Santos; Ana L.

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